The DREAM4 in silico challenge was associated with the DREAM4 conference, held at the Broad Institute of MIT and Harvard in December 2009. There were 33 participating teams, which submitted a total of 300 network predictions for the various benchmark networks of the challenge.
As in the DREAM3 challenges, participants were asked to infer network structures from the given in silico gene expression datasets. In addition, we encouraged participants to use their inferred models to predict the response of the networks to novel perturbations in an optional "bonus round" of the challenge. A detailed description and the results of the challenge are available on the DREAM website:
Videos of DREAM4 presentations are available in the NYAS eBriefing:
The following archive contains all challenges (datasets + gold standards) as available on the DREAM website, plus additional information (additional datasets, the datasets without noise, details on the applied perturbations, the signed goldstandards, network graphs in EPS format, etc). See the pdf file for details: